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Don't let ANA IFA testing spook you

Oct 28, 2022

Eliminate the scary number of negative resultsin just two clicks with ZEUS dIFine®

As the rise in autoimmunity cases increases1, so does the amount of antinuclear antibody testing (ANA) by indirect immunofluorescent assay (IFA). The American College of Rheumatology considers ANA IFA testing using HEp-2 cells the gold standard for ANA screening. Beyond the negative and positive results, ANA pattern determinations provide direction for additional testing to assist the physician to reach a diagnosis.


Focus on the positives and lave the scary negatives behind 


Typically, during ANA screening, a large proportion of results are negative.  ZEUS dIFine saves you time by quickly allowing you to batch, review and validate negative results allowing you to focus your attention on the positives.

Two clicks to batch and validate negative results

  1. Select Negative Filter to review negative wells
  2. Validate all negative results


ZEUS is defining the future of IFA imaging 

ZEUS dIFine is the next generation in IFA imaging and pattern recognition. An automated digital scanner with intelligent software, it is designed to acquire, analyze, display and store digital images of ZEUS HEp-2 IFA slides*. ZEUS is taking your ANA IFA testing to the next level by pairing our top tier IFA ANA HEp-2 products with our dIFine system and quickly delivering positive/negative results and interpretation of 8 distinct ANA HEp-2 patterns:

  • homogenous
  • speckled
  • centromere
  • nucleolar
  • nuclear dots
  • nuclear membrane
  • cytoplasmic (ribosomal)
  • cytoplasmic (mitochondrial)
Learn how to save time with ZEUS dIFine! Schedule your demo today!

There is so much more to see.

Schedule your in-person or virtual dIFine demo today! Contact our sales team and learn more at www.zeusscientific.com/difine.



The ZEUS Scientific Team


1 Reference:  Increasing Prevalence of Antinuclear Antibodies in the United States GE. Dinse et al. Arthritis Rheumatol. 2020 June; 72(6): 1026-1035. Foi. 10.1002/art/41214

*FDA 510(k) cleared. All suggested results obtained with ZEUS dIFine must be confirmed by a trained operator.

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